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Rome in three days: A detailed Hop-on Hop-off itinerary

Exploring Rome is like walking through a museum the size of an entire city. And the Hop-on Hop-off tours are the best way to experience the Eternal City’s history, culture, folklore and of course, the food! Simply hop off to explore a charming piazza, a bustling market, or a hidden trattoria, and when you're ready, hop back on to continue your journey. 

There for three days? We’ve got your back with this itinerary which is perfectly aligned with Hop-on Hop-off routes to help you make the most of your 72 hours in Rome.

Day 1 - Art meets faith!

Start the day at Rome Termini with a healthy dose of authentic Italian breakfast of cornetto & biscotti along with a smooth coffee - to keep energy high. Then take the Hop-on Hop-off bus from the Termini stop straight to Vatican City, the heart of the Catholic Church.

Vatican Museums & Sistine Chapel

St. Peter's Basilica

You can sample restaurants like Il Segreto, Rione XIV Bistrot, Pastasciutta, and Bonci Pizzarium near the Vatican, or walk along the Tiber River, past the mighty Castel Sant’ Angelo. We recommend the latter for a more picturesque setting.

Via Condotti & Spanish Steps

  • Nearest Hop-on Hop-off bus stop: Ludovisi/Spanish Steps (Big Bus), Piazza di Spagna (City Sightseeing), Villa Borghese (Green Line), Spanish Steps (I Love Rome), Popolo Square (Rome Hop-on Hop-off Boat)

The iconic steps connecting the Piazza di Spagna and the Trinità dei Monti Church became a hit with tourists, ever since being featured in the Audrey Hepburn-starrer, Roman Holiday (1953). It is the perfect destination for soaking in Rome’s lively atmosphere, high-end shopping, and sunset views. The Steps also have a special connection with English Romanticism. 

  • Average time to spend: 1.5 hours
  • Opening hours: Open 24/7
  • Pro-tip: Do not sit on the Spanish Steps as much as you want that insta-worthy picture, as it will attract a big fine.

Ginger - Spagna, Angie’s Restaurant, Osteria Barberini, and Taverna Ripetta are some great eateries nearby. Alternatively, you can also grab dinner and drinks from the Piazza Navona, one of Rome’s most beautiful squares. The place lights up at night with a vibrant energy, street artists, and skillfully carved fountains.

Day 2: Walking through time & exploring Rome’s ancient ruins

The Colosseum

Roman Forum

Palatine Hill

Boost your energy levels with La Taverna dei Fori Imperiali’s toasted Crostini, flavorful Cacio e Pepe, and classic Tiramisu. Alternatively, you can check out the various pizzerias, cafés and gelaterias near the Roman baths for a leisurely lunch.

Baths of Caracalla

Circus Maximus

Alternatively, you can trot down to the vibrant neighborhood of Testaccio post your expedition to the Roman baths. Known for its authentic street food and thriving nightlife, this cultural hotspot allows you to experience Rome as a local. Don’t forget to take a riverside walk by the Tiber River.

Day 3: Hidden gems & unique experiences

Basilica of Santa Maria Maggiore

  • Nearest Hop-on Hop-off bus stop: Basilica di Santa Maria Maggiore (Big Bus), S.Maria Maggiore (City Sightseeing), Santa Maria Maggiore (Green Line), Santa Maria Maggiore (I Love Rome), Isola Tiberina (Rome Hop-on Hop-off Boat)

One of Rome’s major basilicas, the Basilica of Santa Maria Maggiore was founded in the 5th century. Start your day by soaking in the serene atmosphere and architectural grandeur at this spiritual haven. This historical monument is also known for housing the relics of the Holy Crib, believed to be from the manger of Jesus.

  • Average time to spend: 30 minutes to 1 hour
  • Opening hours: 7am to 7pm (last entry at 6:30pm)
  • Pro tip: Avoid wearing shorts or sleeveless outfits as a sign of respect and to ensure you aren’t denied entry to the basilica.

Celebrated every 25 years marking a special year of forgiveness, pilgrimage, and renewal of faith, participate in the Jubilee 2025.

Find out more details here.

National Roman Museum

  • Nearest Hop-on Hop-off bus stop: Basilica di Santa Maria Maggiore (Big Bus), S.Maria Maggiore (City Sightseeing), Santa Maria Maggiore (Green Line), Santa Maria Maggiore (I Love Rome), Isola Tiberina (Rome Hop-on Hop-off Boat)

Spread across the 4 distinct sites of the Palazzo Massimo, Palazzo Altemps, Crypta Balbi, and the Baths of Diocletian, the museum showcases an impressive array of sculptures, frescoes, mosaics, and artifacts. Each site presents a different facet of Roman history, from the imperial grandeur to the daily lives of ordinary citizens.

  • Average time to spend: 1 to 2 hours
  • Opening hours: 9:30am to 7pm (Tuesday - Sunday)
  • Closed on: Mondays, January 1 and December 25
  • Pro tip: Visit the Museum shop to find some unique mementos and Roman souvenirs.

Known for its exceptional bread and pastries, visit Panella that is located near the basilica for some refreshments. Their Cornetti (Italian croissants), Pane Casereccio (traditional bread) and Pizza Bianca come highly recommended.

Piazza Venezia & Altar of the Fatherland

Pantheon

There are many interesting options you could explore for lunch around the area like Enoteca Corsi (a charming, family-run spot), Gusto (modern Italian) or Roscioli Salumeria con Cucina (part deli/part restaurant). With your hearts and stomachs full, toss a coin at the Trevi Fountain nearby or marvel at the Baroque fountains at Piazza Navona.

Santa Maria della Vittoria

  • Nearest Hop-on Hop-off bus stop: Piazza Barberini/Spanish Steps (Big Bus), Piazza Barberini (City Sightseeing), Barberini Square (Green Line), Piazza Barberini and Trevi Fountain (I Love Rome), Popolo Square (Rome Hop-on Hop-off Boat)

Completed in 1620, this stunning church is renowned for housing Bernini’s Ecstasy of Saint Teresa, one of the most famous sculptures of the Baroque era. It was famously featured in the film Angels & Demons (2009), based on the book by Dan Brown.

  • Average time to spend: 30 to 45 minutes
  • Opening hours: 8:30am - 12pm; 4pm - 6pm (timings differ on Sundays & special occasions)
  • Closed on: January 1, Easter Sunday and December 25
  • Pro tip: Carry small change as some parts of the church may require coins to illuminate the artwork. This involves inserting a coin into a slot machine that controls the lighting.

Post this you can enjoy a fun stroll to the majestic Piazza della Repubblica, enjoy dinner at a local trattoria and treat yourself to some of Rome’s finest gelato at La Romana. 

Mix it up!

If you have time left, we recommend adding these stops to your itinerary:

  • Baths of Diocletian: A short walk from the Papal Basilica of Saint Mary Major, the site offers insights into Rome’s social practices and urban planning.
  • Quirinale Palace: Serving as the official residence of the President of Italy, the palace features stunning Baroque and neoclassical architecture, with beautifully landscaped gardens.
  • Mamertine Prison: Situated near the Roman Forum, it served as a maximum-security prison for political enemies and war captives.
  • Trastevere: A vibrant market square, it offers a rich blend of history, culture, and local life, making it a fascinating area to delve into. Check out the offbeat murals and creative graffiti too.
  • Aventine Hill: Enjoy the keyhole view through the Knights of Malta gate for a picturesque view of Rome’s sprawling cityscape and historic buildings.
  • Centrale Montemartini: A fascinating museum which creatively integrates Roman columns and statues alongside early 20th-century power plant equipment, ancient statues and artifacts.
  • Roman Catacombs: Fascinating and eerie underground burial tunnels that stretch for miles beneath the city. Decorated with ancient frescoes and inscriptions, the catacombs offer a unique glimpse into the community's life, beliefs, and rituals.